Blood lipid profile
Research suggests cheese fat raises LDL cholesterol less than butter supplying the same amount of saturated fat, an effect repeatedly seen in controlled feeding trials and usually attributed to the cheese matrix. It still raises LDL relative to unsaturated plant oils, so this is a comparison between two saturated-fat sources rather than a benefit.
What may be going on: The calcium and protein matrix of cheese appears to bind fatty acids and increase faecal fat loss, blunting the lipid response relative to the same fat eaten as butter.
Moderate evidence. Several human studies point the same way, with real caveats.
4 sources
- Effect of cheese consumption on blood lipids: a systematic review and meta-analysis of randomized controlled trials.(opens in a new tab)
Meta-analysis · Nutrition reviews · 2015 · PMID 26011901
- Effect of Isoenergetic Substitution of Cheese with Other Dairy Products on Blood Lipid Markers in the Fasted and Postprandial State: An Updated and Extended Systematic Review and Meta-Analysis of Randomized Controlled Trials in Adults.(opens in a new tab)
Meta-analysis · Advances in nutrition (Bethesda, Md.) · 2023 · PMID 37717700
- Milk and dairy consumption and risk of cardiovascular diseases and all-cause mortality: dose-response meta-analysis of prospective cohort studies.(opens in a new tab)
Meta-analysis · European journal of epidemiology · 2017 · PMID 28374228
- The impact of sex and the cheese matrix on cholesterol metabolism in middle-aged adults.(opens in a new tab)
Randomised controlled trial · Atherosclerosis · 2025 · PMID 39923541
Deep research mode adds each paper’s own conclusion and stated limitations.