Blood lipid profile
Research suggests dairy fat raises LDL cholesterol relative to unsaturated plant oils in controlled feeding trials, and ghee is dairy fat with the water taken out. That is a statement of direction rather than a benefit, and it is among the better-replicated findings in diet and lipid research.
What may be going on: Palmitic and myristic acid, both abundant in butterfat, reduce hepatic LDL receptor activity and slow LDL clearance.
Moderate evidence. Several human studies point the same way, with real caveats.
2 sources
- Effects of diets rich in ghee or olive oil on cardiometabolic risk factors in healthy adults: a two-period, crossover, randomised trial.(opens in a new tab)
Randomised controlled trial · The British journal of nutrition · 2022 · PMID 34794522
- Biomarkers of dairy fat intake, incident cardiovascular disease, and all-cause mortality: A cohort study, systematic review, and meta-analysis.(opens in a new tab)
Meta-analysis · PLoS medicine · 2021 · PMID 34547017
Deep research mode adds each paper’s own conclusion and stated limitations.