Blood lipid profile
Meta-analyses of randomised trials consistently show psyllium lowers LDL cholesterol by around 6–7% at doses near 10 g/day, in people on standard diets and in those already taking statins. It is one of the few dietary supplements with an authorised health claim from a regulator that reviewed the evidence.
What may be going on: The viscous gel binds bile acids and limits their reabsorption in the ileum, so the liver draws on circulating cholesterol to replace them.
Strong evidence. Consistent findings across multiple good-quality human studies.
View the 3 sources
- Effect of psyllium (Plantago ovata) fiber on LDL cholesterol and alternative lipid targets, non-HDL cholesterol and apolipoprotein B: a systematic review and meta-analysis of randomized controlled trials.(opens in a new tab)
Meta-analysis · The American journal of clinical nutrition · 2018 · PMID 30239559
- Psyllium is a natural nonfermented gel-forming fiber that is effective for weight loss: A comprehensive review and meta-analysis.(opens in a new tab)
Meta-analysis · Journal of the American Association of Nurse Practitioners · 2023 · PMID 37163454
- Plantago consumption significantly reduces total cholesterol and low-density lipoprotein cholesterol in adults: A systematic review and meta-analysis.(opens in a new tab)
Meta-analysis · Nutrition research (New York, N.Y.) · 2024 · PMID 38688104
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