Digestive comfort
Small randomised trials report reductions in bloating, abdominal pain and stool frequency scores in irritable bowel syndrome. The trials are few, small and supplier-funded, and independent replication is limited.
Limited evidence. Early human work, or mostly lab and animal research.
View the 4 sources
- The effects of Bacillus coagulans MTCC 5856 on functional gas and bloating in adults: A randomized, double-blind, placebo-controlled study.(opens in a new tab)
Randomised controlled trial · Medicine · 2023 · PMID 36862903
- Efficacy of Bacillus coagulans Unique IS2 in treatment of irritable bowel syndrome in children: a double blind, randomised placebo controlled study.(opens in a new tab)
Randomised controlled trial · Beneficial microbes · 2018 · PMID 29695183
- Bacillus coagulans MTCC 5856 supplementation in the management of diarrhea predominant Irritable Bowel Syndrome: a double blind randomized placebo controlled pilot clinical study.(opens in a new tab)
Randomised controlled trial · Nutrition journal · 2016 · PMID 26922379
- Bacillus coagulans Unique IS2 in Constipation: A Double-Blind, Placebo-Controlled Study.(opens in a new tab)
Randomised controlled trial · Probiotics and antimicrobial proteins · 2020 · PMID 30911991
Deep research mode adds each paper’s own conclusion and stated limitations.