Blood lipid profile
Pooled small trials report modest reductions in total and LDL cholesterol. The trials are short, small and often industry-supported, and the effect is well below what lipid-lowering medication achieves.
What may be going on: Luteolin has been reported to inhibit cholesterol synthesis in hepatocyte models, and the extract increases bile flow.
Limited evidence. Early human work, or mostly lab and animal research.
View the 4 sources
- WITHDRAWN: Artichoke leaf extract for treating hypercholesterolaemia.(opens in a new tab)
Meta-analysis · The Cochrane database of systematic reviews · 2016 · PMID 27195440
- Artichoke leaf extract for treating hypercholesterolaemia.(opens in a new tab)
Meta-analysis · The Cochrane database of systematic reviews · 2013 · PMID 23543518
- Artichoke leaf extract for treating hypercholesterolaemia.(opens in a new tab)
Meta-analysis · The Cochrane database of systematic reviews · 2009 · PMID 19821306
- Artichoke leaf extract for treating hypercholesterolaemia.(opens in a new tab)
Systematic review · The Cochrane database of systematic reviews · 2002 · PMID 12137691
Deep research mode adds each paper’s own conclusion and stated limitations.