Blood lipid profile
Meta-analyses of sesame consumption trials report small reductions in total and LDL cholesterol. The trials are mostly small, several used sesame oil or extracted lignans rather than tahini, and heterogeneity is considerable.
What may be going on: Sesame lignans and phytosterols appear to reduce cholesterol absorption in the gut, and sesamin has been reported to affect hepatic lipid handling.
Moderate evidence. Several human studies point the same way, with real caveats.
3 sources
- The Effects of Sesamin Supplementation on Obesity, Blood Pressure, and Lipid Profile: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.(opens in a new tab)
Meta-analysis · Frontiers in endocrinology · 2022 · PMID 35311241
- Effect of sesame supplementation on body composition and lipid profile in patients with type 2 diabetes: A systematic review and meta-analysis of randomized controlled trials.(opens in a new tab)
Meta-analysis · Nutrition, metabolism, and cardiovascular diseases : NMCD · 2024 · PMID 38316576
- Sesame fractions and lipid profiles: a systematic review and meta-analysis of controlled trials.(opens in a new tab)
Meta-analysis · The British journal of nutrition · 2016 · PMID 26758593
Deep research mode adds each paper’s own conclusion and stated limitations.