Endothelial function
Some trials of grape products report improved flow-mediated dilation, most often using concentrated grape juice or grape seed extract rather than whole fruit. Results across trials are inconsistent.
Limited evidence. Early human work, or mostly lab and animal research.
3 sources
- The effect of grape (Vitis vinifera) seed extract supplementation on flow-mediated dilation, blood pressure, and heart rate: A systematic review and meta-analysis of controlled trials with duration- and dose-response analysis.(opens in a new tab)
Meta-analysis · Pharmacological research · 2022 · PMID 34798267
- The effect of whole grape products on blood pressure and vascular function: A systematic review and meta-analysis of randomized controlled trials.(opens in a new tab)
Meta-analysis · Nutrition, metabolism, and cardiovascular diseases : NMCD · 2023 · PMID 37482483
- Meta-Analysis of the Effects of Foods and Derived Products Containing Ellagitannins and Anthocyanins on Cardiometabolic Biomarkers: Analysis of Factors Influencing Variability of the Individual Responses.(opens in a new tab)
Meta-analysis · International journal of molecular sciences · 2018 · PMID 29495642
Deep research mode adds each paper’s own conclusion and stated limitations.