DNA and cellular integrity
A small number of human feeding studies report changes in DNA damage markers and in the activity of phase II conjugating enzymes after several weeks of Brussels sprouts. This is preliminary biomarker research on small groups.
Limited evidence. Early human work, or mostly lab and animal research.
4 sources
- Effects of consumption of Brussels sprouts on intestinal and lymphocytic glutathione S-transferases in humans.(opens in a new tab)
Randomised controlled trial · Carcinogenesis · 1995 · PMID 7554064
- Glutathione S-transferase M1 polymorphism and metabolism of sulforaphane from standard and high-glucosinolate broccoli.(opens in a new tab)
Randomised controlled trial · The American journal of clinical nutrition · 2005 · PMID 16332662
- Oral sulforaphane increases Phase II antioxidant enzymes in the human upper airway.(opens in a new tab)
Clinical trial · Clinical immunology (Orlando, Fla.) · 2009 · PMID 19028145
- Effect of Brussels sprouts on oxidative DNA-damage in man.(opens in a new tab)
Randomised controlled trial · Cancer letters · 1997 · PMID 9103270
Deep research mode adds each paper’s own conclusion and stated limitations.