Blood lipid profile
Evidence is limited. Small trials of wheat germ or its policosanol and phytosterol fractions report inconsistent effects on cholesterol, and the better-designed studies tend to find less than the early ones did.
Limited evidence. Early human work, or mostly lab and animal research.
4 sources
- Policosanol is ineffective in the treatment of hypercholesterolemia: a randomized controlled trial.(opens in a new tab)
Randomised controlled trial · The American journal of clinical nutrition · 2006 · PMID 17158441
- Beneficial Effect of Cuban Policosanol on Blood Pressure and Serum Lipoproteins Accompanied with Lowered Glycated Hemoglobin and Enhanced High-Density Lipoprotein Functionalities in a Randomized, Placebo-Controlled, and Double-Blinded Trial with Healthy Japanese.(opens in a new tab)
Randomised controlled trial · International journal of molecular sciences · 2023 · PMID 36982259
- Meta-analysis of natural therapies for hyperlipidemia: plant sterols and stanols versus policosanol.(opens in a new tab)
Meta-analysis · Pharmacotherapy · 2005 · PMID 15767233
- Effects of policosanol and lovastatin on lipid profile and lipid peroxidation in patients with dyslipidemia associated with type 2 diabetes mellitus.(opens in a new tab)
Randomised controlled trial · International journal of clinical pharmacology research · 2002 · PMID 12837046
Deep research mode adds each paper’s own conclusion and stated limitations.