Inflammatory markers
Meta-analyses report reductions in circulating C-reactive protein and interleukin-6 with curcumin supplementation. These are concentrated extract doses rather than the spice, heterogeneity between trials is high, and whether shifting these markers corresponds to anyone feeling different is untested.
Moderate evidence. Several human studies point the same way, with real caveats.
3 sources
- Antioxidant and anti-inflammatory effects of curcumin/turmeric supplementation in adults: A GRADE-assessed systematic review and dose-response meta-analysis of randomized controlled trials.(opens in a new tab)
Meta-analysis · Cytokine · 2023 · PMID 36804260
- The Effects of Curcumin on Diabetes Mellitus: A Systematic Review.(opens in a new tab)
Systematic review · Frontiers in endocrinology · 2021 · PMID 34012421
- Effect of curcumin on rheumatoid arthritis: a systematic review and meta-analysis.(opens in a new tab)
Meta-analysis · Frontiers in immunology · 2023 · PMID 37325651
Deep research mode adds each paper’s own conclusion and stated limitations.