Blood lipid profile
Evidence is limited and concerns the oil rather than the seed. Replacing saturated fat with linoleic-rich oils, safflower among them, lowers LDL cholesterol in controlled feeding trials, but the whole kernel has not been tested and is barely eaten.
Limited evidence. Early human work, or mostly lab and animal research.
2 sources
- Re-evaluation of the traditional diet-heart hypothesis: analysis of recovered data from Minnesota Coronary Experiment (1968-73).(opens in a new tab)
Meta-analysis · BMJ (Clinical research ed.) · 2016 · PMID 27071971
- Linoleic acid intake and cancer risk: a review and meta-analysis.(opens in a new tab)
Meta-analysis · The American journal of clinical nutrition · 1998 · PMID 9665108
Deep research mode adds each paper’s own conclusion and stated limitations.