Immune function
Evidence is limited and contested. Several small trials of elderberry extract report shorter or milder cold and influenza symptoms, and pooled analyses of them are positive, but the trials are small, most are funded by product makers, and a later independent trial in influenza found no benefit. This is best read as an open question rather than a settled one.
Limited evidence. Early human work, or mostly lab and animal research.
4 sources
- Black elderberry (Sambucus nigra) supplementation effectively treats upper respiratory symptoms: A meta-analysis of randomized, controlled clinical trials.(opens in a new tab)
Meta-analysis · Complementary therapies in medicine · 2019 · PMID 30670267
- Elderberry for prevention and treatment of viral respiratory illnesses: a systematic review.(opens in a new tab)
Systematic review · BMC complementary medicine and therapies · 2021 · PMID 33827515
- Elderberry Supplementation Reduces Cold Duration and Symptoms in Air-Travellers: A Randomized, Double-Blind Placebo-Controlled Clinical Trial.(opens in a new tab)
Randomised controlled trial · Nutrients · 2016 · PMID 27023596
- Randomized study of the efficacy and safety of oral elderberry extract in the treatment of influenza A and B virus infections.(opens in a new tab)
Randomised controlled trial · The Journal of international medical research · 2004 · PMID 15080016
Deep research mode adds each paper’s own conclusion and stated limitations.